The value that's set to `innerHTML` should come from trusted sources, since Javascript will put anything inside that element and it will be run as plain HTML.
Example:
Setting a "`<script>alert();</script>`" value will cause the Javascript "alert()" function to be fired:
```javascript
var element = document.getElementById("demo");
element.innerHTML = "<script>alert();</script>";
```
This type of attack is called [Cross Site Scripting, or XSS for short](https://en.wikipedia.org/wiki/Cross-site_scripting).
This is one of the most common ways of committing an XSS attack. If you want to learn a little bit more and learn to defend against it, [check out this resource](https://xss-game.appspot.com/)